Cellcrusher : What floorutions for broyer the samples in conditions cryogéniques?

Cellcrusher designs a cryogenic grinding tool made of stainless steel, purpose-built for sample preparation in proteomics, genomics and metabolomics. Cooled with liquid nitrogen, it pulverises tissues and tough matrices without thawing, delivering high, reproducible yields. Engineered for life sciences laboratories, R&D facilities and quality control.

A field-ready solution that’s become a benchtop standard

Born from real-world needs in experimental biology, Cellcrusher focuses on a single mission: making cryogenic grinding reliable, fast and reproducible. The brand designs and manufactures in Ireland a rugged tool that meets the day-to-day demands of preparing delicate samples. By prioritising solid stainless steel, straightforward ergonomics and optimised impact surfaces, it has earned the trust of academic and industrial laboratories working on proteins, DNA/RNA and metabolites. This focused, no-nonsense approach has established Cellcrusher as the natural choice for anyone aiming for a fine, homogeneous powder, even from hard or fibrous tissues—without compromising the integrity of target analytes.

Expertise and fields of specialisation

Cellcrusher’s expertise is entirely focused on ultra-low-temperature sample preparation. Chilled in a liquid-nitrogen bath, the tool harnesses the thermal mass of 316L stainless steel to keep tissue frozen during pulverisation. The outcome is a fine, dry powder—ideal for extracting proteins (including phosphoproteins), nucleic acids (DNA/RNA) and metabolites—without artefacts from freeze–thaw cycling. The device excels with demanding matrices (fibrous animal tissues, plant material, compacted yeast) and sample masses from a few milligrams up to several hundred milligrams, typical of proteomics and molecular biology workflows.

Engineered for reproducibility, the design prioritises smooth impact surfaces and simple kinematics to deliver uniform grinding. The 316L stainless steel construction ensures durability, chemical compatibility and supports autoclaving, while making cleaning straightforward. This blend—controlled cold, direct mechanics and premium materials—explains why Cellcrusher is trusted by R&D teams, QC labs and analytical platforms looking for a robust, fast and standardisable sample-prep workflow.

For labs focused on sustainability, the reusable design cuts single-use consumables and cleaning time, without compromising performance.

Cellcrusher products distributed by Dutscher

Frequently asked questions about the Cellcrusher brand

What is the Cellcrusher tool used for?
For cryogenic grinding of samples to extract proteins, DNA/RNA and metabolites, while limiting thawing and improving yield and reproducibility.

What types of samples can be processed?
Animal and plant tissues, yeast or dense biofilms. Ideal when the matrix is hard, fibrous or heat-sensitive, for sample masses from a few mg up to several hundred mg.

Is the equipment compatible with LN2?
Yes. It is designed to be pre-chilled and used in/near a liquid nitrogen (LN2) bath, so the sample stays frozen during grinding.

How do you clean and sterilise the tool?
Made of 316L stainless steel, it is easy to clean (detergents, suitable solvents) and is autoclavable. Grinding bags help minimise cross-contamination.

What is the advantage over a traditional mortar and pestle?
High thermal mass, straightforward handling and optimised contact surfaces deliver a finer powder, less warming and more reproducible results.