Spectrum : Quelles floorutions of dialysis and of tangential flow filtration for the life sciences ?

Spectrum, a Repligen brand, puts the power of membranes to work for the life sciences. From protein dialysis to tangential flow filtration (TFF), it offers solutions for concentration, buffer exchange and clarification, from bench to pilot scale. Well-known products such as Spectra/Por membranes and KrosFlo systems support researchers and biotech and pharma teams in their drive for reproducibility, yield and ease of use, with controlled scalability and comprehensive quality documentation. Modules with hollow fibres and matching consumables form a coherent ecosystem, optimised to reduce volumes, hands-on time and the risk of cross-contamination.

From Spectrum Laboratories to Repligen: the journey of a market leader

Born at the bench and recognised for its dialysis membranes and hollow-fibre modules, Spectrum has shaped decades of sample purification and preparation practice. Joining the Repligen group has elevated that know-how: greater manufacturing capacity, stronger global reach, and innovation fuelled by R&D grounded in real-world use. The classic Spectra/Por range has evolved to offer more MWCO options and formats, while the TFF portfolio has been organised around interoperable systems and consumables. Driven by quality, traceability and performance, the brand now blends deep heritage with modern bioprocess standards to serve research, process development and regulated environments.

Expertise and Areas of Specialisation

Spectrum’s expertise spans two complementary pillars. First, dialysis with Spectra/Por membranes, the laboratory standard for desalting, buffer exchange and gentle purification of biomolecules. A wide choice of MWCOs and diameters, low-adsorption chemistry and convenient formats (tubing, bags, ready-to-use devices) make it straightforward to develop reproducible assays, whether for proteins, nucleic acids or delicate nanoparticles.

Second, tangential flow filtration (TFF) with hollow-fibre modules and KrosFlo systems to concentrate and diafilter gently. The low-shear geometry protects the integrity of fragile species (antibodies, viral vectors, vesicles) while delivering stable flux and controlled scale-up, from micro-volume to pilot. Consistent active surface area and specifications across module sizes de-risk scale-up with no surprises.

Why do labs choose Spectrum? For reliable performance, ease of use (clear set-ups, matched accessories), scalability and strong documentation (batch traceability, technical files and compatibility charts). In practice: concentrate an antibody before chromatography, switch buffer quickly for an enzyme, clarify a cell culture, or reduce volume before analysis — the Spectrum ecosystem brings productivity, control and robustness together at the bench and during process development.

Spectrum products distributed by Dutscher

Frequently asked questions about the Spectrum brand

How do I choose the right MWCO for Spectra/Por dialysis?
As a rule of thumb, pick an MWCO that is three to six times lower than the molecular weight of your molecule of interest. This maximises target retention while speeding up the exchange of low-molecular-weight species.

Are Spectrum TFF modules suitable for delicate biomolecules?
Yes. The hollow-fibre design delivers low shear and stable gradients, ideal for antibodies, vesicles and vectors, with linear, predictable scale-up.

Are the products supplied sterile?
Depending on the catalogue number: some consumables ship sterile, others are sterilisable (e.g. by autoclave or irradiation where stated). Refer to the datasheet for each product.

What guarantees and quality documents are available?
Every lot comes with traceability and quality documentation (e.g. certificates, compatibility information). Dutscher can provide, on request, the files required for your internal audits.

Do KrosFlo systems integrate easily into the laboratory?
The systems are designed for intuitive, modular use, with matched accessories and standardised protocols, to reduce set-up time and increase the robustness of results.