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Laboratory reagent reservoirs: how can multichannel pipetting and robotics be supplied with minimal dead volume?

Whether you’re dispensing buffer across 96 wells or supplying an automated liquid handler, reagent reservoirs ensure clean, swift and reproducible transfer. Designed for multichannel pipetting and robotics, they minimise dead volume thanks to pyramidal or sloped bases. Available in clear polystyrene (PS) or solvent-resistant polypropylene (PP), sterile or non-sterile, graduated, with lids, they safeguard your ELISA and PCR setups, wash steps and serial dispensing. Low-retention surface treatments limit protein and enzyme losses, while disposable inserts on a reusable base reduce your plastic footprint.

What are the different types of reagent reservoirs?

Two main families cover most needs. The standard reagent reservoir makes manual multichannel pipetting straightforward. With a single trough (25 to 300 mL), it is available in clear PS for easy reading, or in PP for chemical resistance (solvents, detergents) and, in some cases, autoclavability. V-bottom or pyramidal bases and low-dead-volume corners maximise recovery of costly reagents (antibodies, enzymes). Sterile, RNase/DNase/pyrogen-free versions with pour spouts, lids and graduations make handling in cell culture and genomics safer.

The robotic reagent reservoir uses the ANSI/SLAS footprint for reliable integration on platforms (Tecan, Hamilton, Beckman, Opentrons…). Internal geometries with low dead volume, low-retention walls and partitions (8 or 12 channels on 9 mm pitch) ensure stable aspiration by automated pipettes. Some models are compatible with temperature modules or anti-evaporation lids to secure long runs.

Key selection criteria:
• Chemical compatibility (PS vs PP) and PP autoclavability.
• Dead volume and recovery (sloped or pyramidal bases, collecting corners).
• Sterility and cleanliness (DNase/RNase/pyrogen-free) according to the application.
• Ergonomics (legible graduations, pour spout, stackability, lids).
• ANSI/SLAS compliance and 8/12-channel compatibility for robotics.
• Sustainability (reusable base plus disposable inserts, recyclable single-material PP).

Below, a comparison table to help you choose:















TypePrincipleApplications
Standard reservoirSingle trough, V/pyramidal base, PS or PPELISA, wash steps, dispensing buffers and media
Compartmentalised 8/12-channelTroughs aligned to 9 mm pitch, multi-reagentMultiplexing, rapid reagent changes
Robotic, low dead volumeANSI/SLAS footprint, low retentionHTS, screening, automated PCR/qPCR

In which applications is a reagent reservoir used?

Essential across life sciences, reservoirs support ELISA (dispense and wash steps), distribution of media for cell culture, and PCR/qPCR set-up (master mix, dyes). In pharma/biotech, they underpin high-throughput screening HTS, aliquoting of libraries and immunoassay workflows. Laboratories for quality control in the food, cosmetics and chemical sectors use them for series of buffers, indicators and solvents. In environment testing, they streamline microplate assays (chemical oxygen demand, colourimetry). On robotised platforms, ANSI/SLAS reservoirs deliver throughput, traceability and fewer human errors, with geometries engineered to minimise evaporation and dead volume — a decisive advantage when reagent is scarce or costly.

Available reagent reservoir types

Frequently asked questions about reagent reservoirs

PS or PP: which should I choose for my application?
PS delivers excellent clarity, ideal for visual checks. PP is more solvent-resistant and, depending on the model, withstands autoclaving. Choose according to the chemistry and sterility requirements.

What is dead volume and how can I reduce it?
It's the liquid that cannot be recovered at the bottom. Opt for pyramidal/sloped bottoms, 'low dead volume' rims and low-retention surfaces. Also adjust the pipette aspiration height.

Are these reservoirs reusable for routine work?
They're designed to minimise cross-contamination and are typically used as single-use items. Reusable bases with inserts cut waste while keeping the safety of a fresh consumable.

Are they compatible with 8/12 channels and robotics?
Yes. Compartmented models align to the 9 mm pitch for 8/12-channel pipettes. ANSI/SLAS formats integrate with robots (Tecan, Hamilton, etc.) without footprint changes.

What guarantee of sterility and cleanliness is there?
Sterile, DNase/RNase/pyrogen-free options are available, often gamma-sterilised. Check the lot certificate for sensitive applications (PCR, cell culture).

How can I limit evaporation during a long run?
Use appropriate lids, work on temperature-controlled areas, and reduce the exposed surface area (compartmented reservoirs).